European Champions Cup: pool-by-pool guide to the weekend games

• Leinster’s Seán O’Brien to miss start of Six Nations after hip operation
• Liam Williams starts for Saracens in make-or-break trip to Ospreys

Chris Robshaw is absent from the Harlequins team to face Wasps after picking up what the club have described as a “minor knock” in training this week. Marcus Smith, fresh from signing a long-term contract with the club, is rested so James Lang makes his Champions Cup debut at fly-half. Wasps, currently third and needing a victory to keep alive their hopes of reaching the knockout stage, are boosted by the return of their captain, Joe Launchbury, to the second row. Kyle Eastmond and Brendan Macken also come into the side in the centres. Christian Lealiifano makes his last home appearance for Ulster against La Rochelle before returning to Australia.

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